Research Progress on Chemical Constituents and Pharmacological Effects of Hawthorn Leaves and Hawthorn Fruit

Author：ZHAO Yue, ZUO Jun, HU Xiaoyang, YU Zining

Unit：School of Basic Medical Sciences, Heilongjiang University of Chinese Medicine, Harbin Heilongjiang 150040, China

Quote：引用：赵悦，左军，胡晓阳，于子柠.山楂叶和山楂果的化学成分及药理作用研究进展[J].中医药导报,2025,31(8):145-151.

DOI：10.13862/j.cn43-1446/r.2025.08.023

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Abstract：

This review summarizes the principal chemical constituents of hawthorn leaves and fruits, including flavonoids, terpenoids and lignans, and elucidates their pharmacological effects in ameliorating insulin resistance, regulating lipid metabolism, exerting antioxidant activity, protecting the cardiovascular system, improving hepatic function, and exerting antitumor effects. Furthermore, it analyzes the potential applications of hawthorn extracts in treating chronic diseases, such as liver disorders, cardiac conditions and diabetes, aiming to provide a theoretical foundation for further development and utilization of hawthorn resources.

Key words：Hawthorn leaves; Hawthorn fruit; chemical composition; pharmacological action; review

摘要：综述山楂叶与山楂果的主要化学成分，包括黄酮类、萜类化合物及木脂素化合物等，并探讨其在干预胰岛素抵抗、调节脂质代谢、抗氧化、保护心血管、改善肝功能及抗肿瘤等方面的药理作用。分析山楂提取物在肝脏疾病、心脏疾病及糖尿病等慢性疾病治疗中的潜在应用，以期为山楂进一步开发与应用提供理论基础。

关键词：山楂叶；山楂果；化学成分；药理作用；综述

Release time：2026-01-06

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