Research Progress on Chemical Constituents and Pharmacological Effects of Liangwangcha (Metapanax delavayi) with Predictive Analysis of Quality Markers (Q-Markers)
Author：CHEN Sinian1, SUN Huacong1, DAI Xiangxian1, XU Zhilin1, TAN Wenhong1,2
Unit：1.School of Ethnic Medicine, Yunnan University of Chinese Medicine, Kunming Yunnan 650500, China; 2.Yunnan Provincial Key Laboratory of Dai Medicine and Yi Medicine, Kunming Yunnan 650000, China
Quote：引用：陈思念，孙华聪，戴相仙，徐志霖，谭文红.梁王茶化学成分、药理作用研究进展及质量标志物(Q－Marker)预测分析[J].中医药导报,2025,31(9):83-90,96.
DOI：10.13862/j.cn43-1446/r.2025.09.014
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Abstract：This review summarizes the research progress on the
chemical constituents, pharmacological effects, and applications of Metapanax
delavayi. Based on the concept of quality markers (Q-markers), a predictive
analysis of its Q-markers was conducted by integrating four aspects:
measurability of chemical constituents, correlation between chemical
constituents and pharmacological effects, traditional medicinal properties, and
efficacy correlation. Metapanax delavayi contains triterpenoid saponins,
phenolic acids, and lignans, along with smaller quantities of other components
such as flavonoids and volatile oils. It exhibits various pharmacological
activities including analgesia, anti-inflammation, antioxidation, inhibition of
prostate hyperplasia, hepatoprotection, antibacterial, antiviral, and
antimalarial effects. Triterpenoid saponins are identified as the primary
active constituents. It is suggested that liangwanoside Ⅱ, yiyeliangwanoside Ⅳ, syringaresinol, quercetin,
kaempferol, catechin, salicylic acid, and cinnamic acid could serve as
potential Q-markers for Metapanax delavayi.
Key words：Liangwangcha (Metapanax delavayi); chemical constituents; pharmacological effects; quality markers (Q-markers)
摘要：
总结梁王茶的化学成分、药理作用及其应用研究进展，并在此基础上结合质量标志物的概念，从化学成分可测性、化学成分与药理作用相关性、传统药性、药效相关性四方面，预测分析梁王茶的质量标志物。梁王茶含有三萜皂苷类、酚酸类、木脂素类化学成分，以及少量黄酮类、挥发油类等其他化学成分，具有镇痛、抗炎、抗氧化、抑制前列腺增生、保肝、抗菌、抗病毒及抗疟等功效。三萜皂苷类为主要药效物质。建议将梁王茶苷Ⅱ、异叶梁王茶苷Ⅳ、丁香脂素、槲皮素、山柰酚、儿茶素、水杨酸和肉桂酸作为梁王茶质量标志物的选择参考。
关键词：梁王茶；化学成分；药理作用；质量标志物
Release time：2026-01-08
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