Research Progress of Tongbian Decoction (通便汤) and Its Derivative Formulae in the Treatment of Functional Constipation

Author：ZHENG Yi1, MIAO Qian1, TANG Yan1, LIU Bailong2

Unit：1.Lanzhou Third People's Hospital, Lanzhou Gansu 730050, China; 2.Gansu Provincial Institute for Drug Control, Lanzhou Gansu 730300, China

Quote：引用：郑义，苗倩，唐艳，刘柏龙.通便汤及其组方类方治疗功能性便秘的研究进展[J].中医药导报,2026,32(2):157-160,178.

DOI：10.13862/j.cn43-1446/r.2026.02.026

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Abstract：

This study analyzes the etiology and pathogenesis of functional constipation and reviews relevant reports on the treatment of functional constipation using Tongbian Decoction and its derivative formulae, key individual herbs, and active components. Functional constipation often arises from emotional disturbances, external pathogens, deficiencies of qi, blood, yin, and yang, and dietary internal injuries, leading to dysfunction in ascending and descending movements, visceral disharmony, impeded lung qi, and qi stagnation. Tongbian Decoction has the effects of warming the kidney, strengthening the spleen, supplementing qi and blood, and resolving stasis to promote defecation. Its derivative formulae [Wenshen Jianpi Tongbian Decoction (温肾健脾通便汤), Huayu Tongbian Decoction (化瘀通便汤), and Liqi Tongbian Formula (理气通便方)] can improve gastrointestinal function, regulate motility, and alleviate symptoms. Key individual herbs in these formulae, such as Dahuang (Rhei Radix et Rhizoma), Baizhu (Atractylodis Macrocephalae Rhizoma), Huangqi (Astragali Radix), Roucongrong (Cistanches Herba), Houpu (Magnoliae Officinalis Cortex), and Zhishi (Aurantii Fructus Immaturus), along with their active components, also hold significant therapeutic value. Tongbian Decoction and its derivative formulae can holistically regulate qi, blood, yin, and yang, improve constitution, and enhance therapeutic efficacy.

Key words：functional constipation; Tongbian Decoction; derivative formulae; mechanism of action; review

摘要：分析功能性便秘的病因病机，并对通便汤及其组方类方、关键单味药及有效成分治疗功能性便秘的相关报道进行综述。功能性便秘多由情志不节、外感邪气、气血阴阳不足、饮食内伤致升降失司、脏腑失调、肺气不利、气机不通。通便汤具有温肾健脾、益气养血、化瘀通便之效，其组方类方（温肾健脾通便汤、化瘀通便汤、理气通便方）可改善胃肠功能、调节动力、缓解症状；方中大黄、白术、黄芪、肉苁蓉、厚朴、枳实及其有效成分亦具有重要治疗意义。通便汤及其类方可整体调理气血阴阳，改善体质，提升疗效。

关键词：功能性便秘；通便汤；类方；作用机制；综述

Release time：2026-03-05

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